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1

Recombinant soluble tumor necrosis factor receptor proteins protect mice from lipopolysaccharide-induced lethality

Werner Lesslauer, Hisahiro Tabuchi, Reiner Gentz, Manfred Brockhaus, Ernst Juergen Schlaeger, Georges Grau, Pierre Francois Piguet, Pascal Pointaire, Pierre Vassalli, Hunsruedi Loetscher

Journal:

European Journal of Immunology

Year:

1991

Language:

english

File:

PDF, 351 KB

english, 1991

2

Crystal structure of the soluble human 55 kd TNF receptor-human TNFβ complex: Implications for TNF receptor activation

David W. Banner, Allan D'Arcy, Wolfgang Janes, Reiner Gentz, Hans-Joachim Schoenfeld, Clemens Broger, Hansruedi Loetscher, Werner Lesslauer

Journal:

Year:

1993

Language:

english

File:

PDF, 6.61 MB

english, 1993

3

T90/44 (9.3 antigen). A cell surface molecule with a function in human T cell activation

Werner Lesslauer, Frits Koning, Tom Ottenhoff, Marius Giphart, Els Goulmy, Jon J. Van Rood

Journal:

European Journal of Immunology

Year:

1986

Language:

english

File:

PDF, 894 KB

english, 1986

4

Independent regulation of 55-kDa and 75-kDa tumor necrosis factor receptors during activation of human peripheral blood B lymphocytes

Bjørn K. Erikstein, Erlend B. Smeland, Heidi Kiil Blomhoff, Steinar Funderud, Kristian Prydz, Werner Lesslauer, Terje Espevik

Journal:

European Journal of Immunology

Year:

1991

Language:

english

File:

PDF, 498 KB

english, 1991

5

Transgenic mice expressing high levels of soluble TNF-R1 fusion protein are protected from lethal septic shock and cerebral malaria, and are highly sensitive to Listeria monocytogenes and Leishmania major infections

Iréne Garcia, Yoshitaka Miyazaki, Kimi Araki, Masatake Araki, Ralf Lucas, Georges E. Grau, Geneviéve Milon, Yasmine Belkaid, Christine Montixi, Werner Lesslauer, Pierre Vassalli

Journal:

European Journal of Immunology

Year:

1995

Language:

english

File:

PDF, 1.01 MB

english, 1995

6

High sensitivity of transgenic mice expressing soluble TNFR1 fusion protein to mycobacterial infections: Synergistic action of TNF and IFN-γ in the differentiation of protective granulomas

Irène Garcia, Yoshitaka Miyazaki, Gilles Marchal, Werner Lesslauer, Pierre Vassalli

Journal:

European Journal of Immunology

Year:

1997

Language:

english

File:

PDF, 9.29 MB

english, 1997

7

The interaction of phospholipase a with lipids. I. Structure of the bimolecular leaflet of a lecithin analogue substance, 1-oleoyl-2-n-hexadecyl-2-deoxyglycero-3-phosphorylcholine

W. Lesslauer, A.J. Slotboom, G.H. De Haas

Journal:

Chemistry and Physics of Lipids

Year:

1973

Language:

english

File:

PDF, 992 KB

english, 1973

8

Molecular cloning and expression of the mouseTnfreceptor type b

Joachim G. Rothe, Manfred Brockhaus, Reiner Gentz, Werner Lesslauer

Journal:

Year:

1991

Language:

english

File:

PDF, 255 KB

english, 1991

9

Modellversuch zur Gaskonzentrierung in der Schwimmblase der Fische

W. Lesslauer, F. Burger, H. J. Kuhn, W. Kuhn

Journal:

Pflügers Archiv European Journal of Physiology

Year:

1966

Language:

german

File:

PDF, 755 KB

german, 1966

10

Purification and N-terminal amino acid sequence of the human T90/44 (CD28) antigen

Werner Lesslauer, Hans Gmünder, Peter Böhlen

Journal:

Year:

1988

Language:

english

File:

PDF, 387 KB

english, 1988

11

Cytokines, receptors, and inhibitors

G. Gehr, T. Braun, W. Lesslauer

Journal:

Journal of Molecular Medicine

Year:

1992

Language:

english

File:

PDF, 588 KB

english, 1992

12

Some Electrical Properties of Bimolecular Phosphatidyl Inositol Membranes

LESSLAUER, W., RICHTER, J., LÄUGER, P.

Journal:

Year:

1967

File:

PDF, 324 KB

1967

13

Human TNF mutants with selective activity on the p55 receptor

Ostade, Xaveer Van, Vandenabeele, Peter, Everaerdt, Bart, Loetscher, Hansruedi, Gentz, Reiner, Brockhaus, Manfred, Lesslauer, Werner, Tavernier, Jan, Brouckaert, Peter, Fiers, Walter

Journal:

Year:

1993

File:

PDF, 461 KB

1993

14

Mice lacking the tumour necrosis factor receptor 1 are resistant to IMF-mediated toxicity but highly susceptible to infection by Listeria monocytogenes

Rothe, Joachim, Lesslauer, Werner, Lötscher, Hansruedi, Lang, Yolande, Koebel, Pascale, Köntgen, Frank, Althage, Alana, Zinkernagel, Rolf, Steinmetz, Michael, Bluethmann, Horst

Journal:

Year:

1993

File:

PDF, 569 KB

1993

15

Tumor necrosis factor receptors-structure and function

Joachim Rothe, Gisela Gehr, Hansruedi Loetscher, Werner Lesslauer

Journal:

Immunologic Research

Year:

1992

Language:

english

File:

PDF, 783 KB

english, 1992

16

A novel rat CC chemokine, identified by targeted differential display, is upregulated in brain inflammation

Ulrike Utans-Schneitz, Hanspeter Lorez, Wolfgang E.F. Klinkert, Jean da Silva, Werner Lesslauer

Journal:

Journal of Neuroimmunology

Year:

1998

Language:

english

File:

PDF, 746 KB

english, 1998

17

Phylogenetic analysis of the vertebrate Excitatory/Neutral Amino Acid Transporter (SLC1/EAAT) family reveals lineage specific subfamilies

Matthias Gesemann, Annegret Lesslauer, Colette M Maurer, Helia B Schönthaler, Stephan CF Neuhauss

Journal:

BMC Evolutionary Biology

Year:

2010

Language:

english

File:

PDF, 3.17 MB

english, 2010

18

A 45-kDa human T-cell membrane glycoprotein functions in the regulation of cell proliferative responses

Hans GMÜNDER, Werner LESSLAUER

Journal:

Year:

1984

Language:

english

File:

PDF, 1.05 MB

english, 1984

19

Crystallization and Preliminary Crystallographic Analysis of a TNF-β-55 kDa TNF Receptor Complex

Allan D'Arcy, David W. Banner, Wolfgang Janes, Fritz K. Winkler, Hansruedi Loetscher, Hans-Joachim Schönfeld, Martin Zulauf, Reiner Gentz, Werner Lesslauer

Journal:

Journal of Molecular Biology

Year:

1993

File:

PDF, 211 KB

1993

20

Electrical properties of bimolecular phospholipid membranes

P. Läuger, W. Lesslauer, E. Marti, J. Richter

Journal:

Biochimica et Biophysica Acta (BBA) - Biomembranes

Year:

1967

Language:

english

File:

PDF, 753 KB

english, 1967

21

Effects of phospholipase A and pre-phospholipase A on black phospholipid membranes

W. Lesslauer, A.J. Slotboom, N.M. Postema, G.H. De Haas, L.L.M. Van Deenen

Journal:

Biochimica et Biophysica Acta (BBA) - Biomembranes

Year:

1968

Language:

english

File:

PDF, 185 KB

english, 1968

22

A hydrocarbon-soluble protein-lipid complex: characterization by chemical analysis, ultracentirfugation and electron microscopy

W. Lesslauer, F.C. Wissler, D.F. Parsons

Journal:

Biochimica et Biophysica Acta (BBA) - Biomembranes

Year:

1970

Language:

english

File:

PDF, 1.07 MB

english, 1970

23

On the location of 1-anilino-8-naphthalene-sulfonate in lipid model systems: An X-ray diffraction study

W. Lesslauer, J. Cain, J.K. Blasie

Journal:

Biochimica et Biophysica Acta (BBA) - Biomembranes

Year:

1971

Language:

english

File:

PDF, 1.16 MB

english, 1971

24

On the structure of agglutinated sheep red blood cell membranes

Journal:

Biochimica et Biophysica Acta (BBA) - Biomembranes

Year:

1976

Language:

english

File:

PDF, 1.20 MB

english, 1976

25

Phytohemagglutinin and transmembrane proteins in agglutinated sheep erythrocyte ghost membranes

Journal:

Biochimica et Biophysica Acta (BBA) - Biomembranes

Year:

1978

Language:

english

File:

PDF, 312 KB

english, 1978

26

(10.5 Å)−1 diffraction and transmembrane proteins of erythrocyte ghost membranes

Journal:

Biochimica et Biophysica Acta (BBA) - Biomembranes

Year:

1980

Language:

english

File:

PDF, 526 KB

english, 1980

27

Human lymphocyte membrane proteins treated with neuraminidase

Hans Gmünder, Peter Lerch, Werner Lesslauer

Journal:

Biochimica et Biophysica Acta (BBA) - Biomembranes

Year:

1982

Language:

english

File:

PDF, 531 KB

english, 1982

28

Two detergent-insoluble proteins of the human lymphocyte membrane are enriched in an isolated membrane fraction

Werner Lesslauer, Peter Lerch, Hans Gmünder

Journal:

Biochimica et Biophysica Acta (BBA) - Biomembranes

Year:

1982

Language:

english

File:

PDF, 914 KB

english, 1982

29

TNF-α receptor fusion protein prevents experimental auto-immune encephalomyelitis and demyelination in Lewis rats: an overview

W.E.F Klinkert, K Kojima, W Lesslauer, W Rinner, H Lassmann, H Wekerle

Journal:

Journal of Neuroimmunology

Year:

1997

Language:

english

File:

PDF, 221 KB

english, 1997

30

Immune response to a recombinant human TNFR55-IgG1 fusion protein: auto-antibodies in rheumatoid arthritis (RA) and multiple sclerosis (MS) patients have neither neutralizing nor agonist activities

Urs Christen, Rana Thuerkauf, Randall Stevens, Werner Lesslauer

Journal:

Human Immunology

Year:

1999

Language:

english

File:

PDF, 1.36 MB

english, 1999

31

Mutations in the Tight-Junction Gene Claudin 19 (CLDN19) Are Associated with Renal Magnesium Wasting, Renal Failure, and Severe Ocular Involvement

Martin Konrad, André Schaller, Dominik Seelow, Amit V. Pandey, Siegfried Waldegger, Annegret Lesslauer, Helga Vitzthum, Yoshiro Suzuki, John M. Luk, Christian Becker, Karl P. Schlingmann, Marcel Schmi

Journal:

The American Journal of Human Genetics

Year:

2006

Language:

english

File:

PDF, 2.76 MB

english, 2006

32

Molecular cloning and expression of the human 55 kd tumor necrosis factor receptor

Hansruedi Loetscher, Yu-Ching E. Pan, Hans-Werner Lahm, Reiner Gentz, Manfred Brockhaus, Hisahiro Tabuchi, Werner Lesslauer

Journal:

Year:

1990

Language:

english

File:

PDF, 1.25 MB

english, 1990

33

Genomic organization and promoter function of the murine tumor necrosis factor receptor β gene

Joachim Rothe, Horst Bluethmann, Reiner Gentz, Werner Lesslauer, Michael Steinmetz

Journal:

Molecular Immunology

Year:

1993

Language:

english

File:

PDF, 1.46 MB

english, 1993

34

Direct Determination of the Structure of Barium Stearate Multilayers by X-Ray Diffraction

Lesslauer, W., Blasie, J.K.

Journal:

Biophysical Journal

Year:

1972

Language:

english

File:

PDF, 768 KB

english, 1972

35

Development of immunoassays for the detection of soluble tumour necrosis factor receptors

Nina-Beate Liabakk, Anders Sundan, Anders Waage, Manfred Brockhaus, Hansruedi Loetcher, Werner Lesslauer, Terje Espevik

Journal:

Journal of Immunological Methods

Year:

1991

Language:

english

File:

PDF, 537 KB

english, 1991

36

Biochemical characterization of the 9.3 antigens of human T-cells: Simultaneous expression of disulfide-bonded 90-kilodalton dimers and free subunits at the cell surface

Werner Lesslauer, Hans Gmünder

Journal:

Molecular Immunology

Year:

1986

Language:

english

File:

PDF, 1.20 MB

english, 1986

37

Identification of a new lymphocyte subset surface antigen, the expression of which disappears after in vitro and in vivo stimulation Distribution, biochemistry, and functional studies

Koning, Frits, Bakker, Arjen, Dubelaar, Mirjam, Lesslauer, Werner, Mullink, Rik, Schuits, Riek, Ligthart, Gerard, Naipal, Albert, Bruning, Hans

Journal:

Human Immunology

Year:

1986

Language:

english

File:

PDF, 1.11 MB

english, 1986

38

Two human TNF receptors have similar extracellular, but distinct intracellular, domain sequences

Dembic, Zlatko, Loetscher, Hansruedi, Gubler, Ueli, Pan, Yu-Ching E., Lahm, Hans-Werner, Gentz, Reiner, Brockhaus, Manfred, Lesslauer, Werner

Journal:

Year:

1990

Language:

english

File:

PDF, 909 KB

english, 1990

39

X-Ray Diffraction Studies of Lecithin Bimolecular Leaflets with Incorporated Fluorescent Probes

W. Lesslauer, J. E. Cain and J. K. Blasie

Journal:

Proceedings of the National Academy of Sciences

Year:

1972

Language:

english

File:

PDF, 762 KB

english, 1972

40

Discussion on “A cathode-ray oscillograph with high-speed drum camera rotating in vacuo” before the North-Eastern Centre, at Newcastle, 13th January, 1936

Drayton, D. L., Ying, X., Lee, J., Lesslauer, W., Ruddle, N. H.

Journal:

Journal of the Institution of Electrical Engineers

Year:

1936

Language:

english

File:

PDF, 323 KB

english, 1936

41

Ectopic LT Directs Lymphoid Organ Neogenesis with Concomitant Expression of Peripheral Node Addressin and a HEV-restricted Sulfotransferase

Drayton, D. L., Ying, X., Lee, J., Lesslauer, W., Ruddle, N. H.

Journal:

Journal of Experimental Medicine

Year:

2003

Language:

english

File:

PDF, 572 KB

english, 2003

42

Identification of two types of tumor necrosis factor receptors on human cell lines by monoclonal antibodies.

Brockhaus, M., Schoenfeld, H. J., Schlaeger, E. J., Hunziker, W., Lesslauer, W., Loetscher, H.

Journal:

Proceedings of the National Academy of Sciences

Year:

1990

Language:

english

File:

PDF, 1.04 MB

english, 1990

43

RSK-B, a Novel Ribosomal S6 Kinase Family Member, Is a CREB Kinase under Dominant Control of p38 Mitogen-activated Protein Kinase (p38 MAPK)

Pierrat, B., Correia, J. d. S., Mary, J.-L., Tomas-Zuber, M., Lesslauer, W.

Journal:

Journal of Biological Chemistry

Year:

1998

Language:

english

File:

PDF, 1.24 MB

english, 1998

44

Tumor Necrosis Factor Receptors (Tnfr) in Mouse Fibroblasts Deficient in Tnfr1 or Tnfr2 are Signaling Competent and Activate the Mitogen-activated Protein Kinase Pathway with Differential Kinetics

Kalb, A., Bluethmann, H., Moore, M. W., Lesslauer, W.

Journal:

Journal of Biological Chemistry

Year:

1996

Language:

english

File:

PDF, 803 KB

english, 1996

45

Pretreatment with a 55‐kDa Tumor Necrosis Factor Receptor‐Immunoglobulin Fusion Protein Attenuates Activation of Coagulation, but not of Fibrinolysis, during Lethal Bacteremia in Baboons

van der Poll, Tom, Jansen, Patty M., Van Zee, Kimberly J., Hack, C. Erik, Oldenburg, Hester A., Loetscher, Hansruedi, Lesslauer, Werner, Lowry, Stephen F., Moldawer, Lyle L.

Journal:

The Journal of Infectious Diseases

Year:

1997

Language:

english

File:

PDF, 138 KB

english, 1997

46

C-terminal Elements Control Location, Activation Threshold, and p38 Docking of Ribosomal S6 Kinase B (RSKB)

Tomas-Zuber, M., Mary, J.-L., Lamour, F., Bur, D., Lesslauer, W.

Journal:

Journal of Biological Chemistry

Year:

2001

Language:

english

File:

PDF, 691 KB

english, 2001

47

Blockade of p38 Mitogen-activated Protein Kinase Pathway Inhibits Inducible Nitric-oxide Synthase Expression in Mouse Astrocytes

Da Silva, J., Pierrat, B., Mary, J.-L., Lesslauer, W.

Journal:

Journal of Biological Chemistry

Year:

1997

Language:

english

File:

PDF, 1003 KB

english, 1997

48

Transgenic LacZ under control of Hec-6st regulatory sequences recapitulates endogenous gene expression on high endothelial venules

Liao, S., Bentley, K., Lebrun, M., Lesslauer, W., Ruddle, F. H., Ruddle, N. H.

Journal:

Proceedings of the National Academy of Sciences

Year:

2007

Language:

english

File:

PDF, 1.41 MB

english, 2007

49

Toxicity in Neuronal Cells Caused by Cerebrospinal Fluid from Pneumococcaland Gram-Negative Meningitis

Tauber, M. G., Sachdeva, M., Kennedy, S. L., Loetscher, H., Lesslauer, W.

Journal:

The Journal of Infectious Diseases

Year:

1992

Language:

english

File:

PDF, 613 KB

english, 1992

50

Control Sites of Ribosomal S6 Kinase B and Persistent Activation through Tumor Necrosis Factor

Tomas-Zuber, M., Mary, J.-L., Lesslauer, W.

Journal:

Journal of Biological Chemistry

Year:

2000

Language:

english

File:

PDF, 814 KB

english, 2000

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